Drug of the Month:
Oxcarbazepine (Trileptal)

What doesn't work can hurt you

Oxcarbazepine chemical structure

Oxcarbazepine is one of the most overrated drugs in psychiatry.  It is used frequently, even though it has little to no scientific basis for being used at all. It’s an anticonvulsant, but psychiatrists generally don't treat epilepsy.  It’s use for psychiatric conditions is questionable at best. 

Why would carbamazepine “work” for mood illnesses, but not oxcarbazepine?

For the same reason that chlorpromazine “works”, but imipramine doesn’t. Literally, the difference between...

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PL Reflection

Windy errors have long been, and will long continue to be, swollen into transient consequence.  

Oliver Wendell Holmes Sr

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