Drug of the Month:
Paroxetine

The lowest risk of mania in bipolar depression, but ineffective


Paroxetine 3D structure


Biological mechanism

Paroxetine is a serotonin reuptake inhibitor which, at low doses, is highly selective for serotonin, but at higher doses, also inhibits norepinephrine reuptake. In general, it’s often thought that  norepinephrine reuptake leads  to increased induction of mania. Thus, the observation of low acute mania induction with paroxetine may be due to...

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PL Reflection


The central fact of psychology is that each one of us stares forth from an individually shaped and genetically determined nervous system into a world seen from this time and place in a way that will never happen again.

Leston Havens 

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